Recombinant Human RAB40C protein (ab163653)

Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MGSQGSPVKSYDYLLKFLLVGDSDVGKGEILESLQDGAAESPYAYSNGID YKTTTILLDGRRVRLELWDTSGQGRFCTIFRSYSRGAQGILLVYDITNRW SFDGIDRWIKEIDEHAPGVPRILVGNRLHLAFKRQVPTEQARAYAEKNCM TFFEVSPLCNFNVIESFTELSRIVLMRHGMEKIWRPNRVFSLQDLCCRAI VSCTPVHLIDKLPLPVTIKSHLKSFSMANGMNAVMMHGRSYSLASGAGGG GSKGNSLKRSKSIRPPQSPPQNCSRSNCKIS
    • Amino acids
      1 to 281
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab163653 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • rab 40C
    • Rab40c
    • RAB40C, member RAS oncogene family
    • RAR (RAS like GTPASE) like
    • RAR like
    • Rar like protein
    • Rar-like protein
    • RARL
    • RAS like GTPase
    • Ras like protein family member 8C
    • RAS like, family 8, member C
    • Ras related protein Rab40C
    • Ras-like protein family member 8C
    • Ras-related protein Rab-40C
    • RASL8C
    • RB40C_HUMAN
    • SOCS box containing protein RAR3
    • SOCS box-containing protein RAR3
    see all
  • Function
    Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
  • Pathway
    Protein modification; protein ubiquitination.
  • Sequence similarities
    Belongs to the small GTPase superfamily. Rab family.
    Contains 1 SOCS box domain.
  • Domain
    The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.
  • Cellular localization
    Cell membrane.
  • Information by UniProt

Images

  • ab163653 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab163653 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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