Recombinant Human RAC2 protein (ab84655)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman

Specifications

Our Abpromise guarantee covers the use of ab84655 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    SDS-PAGE

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: 150mM Imidazole
    Constituents: 25% Glycerol, 50mM Sodium phosphate, 300mM Sodium chloride, 2mM DTT, 0.1mM PMSF, pH 7.0

General Info

  • Alternative names
    • EN 7
    • EN-7
    • EN7
    • GX
    • HSPC 022
    • HSPC022
    • p21 Rac 2
    • p21 Rac2
    • p21-Rac2
    • p21Rac2
    • RAC 2
    • Rac2
    • RAC2_HUMAN
    • Ras related C3 botulinum toxin substrate 2
    • Ras related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2
    • Ras related C3 botulinum toxin substrate 3
    • Ras related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac2)
    • Ras-related C3 botulinum toxin substrate 2
    • Rho family small GTP binding protein Rac 2
    • Rho family small GTP binding protein Rac2
    • Small G protein
    see all
  • FunctionPlasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.
  • Tissue specificityHematopoietic specific.
  • Involvement in diseaseDefects in RAC2 are the cause of neutrophil immunodeficiency syndrome (NEUID) [MIM:608203].
  • Sequence similaritiesBelongs to the small GTPase superfamily. Rho family.
  • Cellular localizationCytoplasm. Membrane-associated when activated.
  • Information by UniProt

Recombinant Human RAC2 protein images

  • SDS-PAGE showing ab84655 at approximately 22kDa.

References for Recombinant Human RAC2 protein (ab84655)

ab84655 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"