Overview

  • Product name
    Recombinant Human RACK1 protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MTEQMTLRGT LKGHNGWVTQ IATTPQFPDM ILSASRDKTI IMWKLTRDET NYGIPQRALR GHSHFVSDVV ISSDGQFALS GSWDGTLRLW DLTTGTTTRR FVGHTKDVLS VAFSSDNRQI VSGSRDKTIK LWNTLGVCKY TVQDESHSEW VSCVRFSPNS SNPIIVSCGW DKLVKVWNLA NCKLKTNHIG HTGYLNTVTV SPDGSLCASG GKDGQAMLWD LNEGKHLYTL DGGDIINALC FSPNRYWLCA ATGPSIKIWD LEGKIIVDEL KQEVISTSSK AEPPQCTSLA WSADGQTLFA GYTDNLVRVW QVTIGTR
    • Molecular weight
      37 kDa including tags
    • Amino acids
      1 to 317
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab119442 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF
  • Purity
    > 95 % SDS-PAGE.
    ab119442 was purified using conventional chromatography.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.08% DTT, 0.32% Tris HCl, 50% Glycerol, 1.17% Sodium chloride

General Info

  • Alternative names
    • Cell proliferation-inducing gene 21 protein
    • GBLP_HUMAN
    • Gnb2-rs1
    • Gnb2l1
    • Guanine nucleotide binding protein (G protein) beta polypeptide 2 like 1
    • Guanine nucleotide binding protein beta polypeptide 2 like 1
    • Guanine nucleotide binding protein beta subunit 2 like 1
    • Guanine nucleotide binding protein beta subunit like protein 12.3
    • Guanine nucleotide binding protein subunit beta 2 like 1
    • Guanine nucleotide binding protein subunit beta like protein 12.3
    • Guanine nucleotide-binding protein subunit beta-2-like 1
    • Guanine nucleotide-binding protein subunit beta-like protein 12.3
    • H12.3
    • HLC-7
    • Human lung cancer oncogene 7 protein
    • lung cancer oncogene 7
    • OTTHUMP00000223704
    • OTTHUMP00000223870
    • OTTHUMP00000223891
    • OTTHUMP00000223893
    • OTTHUMP00000223900
    • OTTHUMP00000223902
    • OTTHUMP00000223930
    • OTTHUMP00000223931
    • PIG21
    • Proliferation inducing gene 21
    • Protein homologous to chicken B complex protein guanine nucleotide binding
    • RACK1
    • Receptor for activated C kinase
    • Receptor for activated C kinase 1
    • Receptor of activated protein kinase C 1
    see all
  • Function
    Seems to bind protein kinase C acting as an intracellular receptor to anchor the activated PKC to the cytoskeleton. May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and ITGB1, serves as a platform for SRC activation or inactivation. May play an important role in the developing brain and neuronal differentiation.
  • Sequence similarities
    Belongs to the WD repeat G protein beta family.
    Contains 7 WD repeats.
  • Domain
    The WD repeats domain 5 mediates interaction with TRIM63.
  • Cellular localization
    Cell membrane. Located on plasma membrane of neuroblastoma NMB7 cells.
  • Information by UniProt

Images

  • 15% SDS-PAGE showing ab119442 at approximately 37.2kDa (3µg).

References

This product has been referenced in:

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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