Recombinant Human RbAp46 protein (ab114396)

Overview

Description

  • NatureRecombinant
  • SourceWheat germ
  • Amino Acid Sequence
    • AccessionQ16576
    • SpeciesHuman
    • SequenceMASKEMFEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLP EVTKPEGKDYALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFDASHCDSD KGEFGGFGSVTGKIECEIKINHEGEVNRARYMPQNPHIIATKTPSSDVLV FDYTKHPAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHT VCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQK LMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALW DLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIG EEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQI WQMAENIYNDEESDVTTSELEGQGS
    • Molecular weight73 kDa including tags
    • Amino acids1 to 425

Specifications

Our Abpromise guarantee covers the use of ab114396 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    ELISA

    Western blot

  • FormLiquid
  • Additional notesProtein concentration is above or equal to 0.05 mg/ml.
    ab114396 is best used within three months from the date of receipt.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

General Info

  • Alternative names
    • G1/S transition control protein binding protein RbAp46
    • Histone acetyltransferase type B subunit 2
    • Histone binding protein RBBP7
    • Histone-binding protein RBBP7
    • MGC138867
    • MGC138868
    • Nucleosome remodeling factor subunit RBAP46
    • Nucleosome-remodeling factor subunit RBAP46
    • RBAP46
    • RBBP 7
    • RBBP-7
    • RBBP7
    • RBBP7_HUMAN
    • Retinoblastoma binding protein 7
    • Retinoblastoma binding protein p46
    • Retinoblastoma-binding protein 7
    • Retinoblastoma-binding protein p46
    • Retinoblastoma-binding protein RbAp46
    see all
  • FunctionCore histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.
  • Sequence similaritiesBelongs to the WD repeat RBAP46/RBAP48/MSI1 family.
    Contains 7 WD repeats.
  • Cellular localizationNucleus.
  • Information by UniProt

Recombinant Human RbAp46 protein images

  • ab114396 analysed on a 12.5% SDS-PAGE Stained with Coomassie Blue.

References for Recombinant Human RbAp46 protein (ab114396)

ab114396 has not yet been referenced specifically in any publications.

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