Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MSSEEGKLFVGGLNFNTDEQALEDHFSSFGPISEVVVVKDRETQRSRGFG FITFTNPEHASVAMRAMNGESLDGRQIRVD
    • Molecular weight
      34 kDa
    • Amino acids
      1 to 80

Specifications

Our Abpromise guarantee covers the use of ab116747 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml. Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

General Info

  • Alternative names
    • 2600016C11Rik
    • IS1 RNPL
    • MGC105811
    • MGC118410
    • OTTHUMP00000025800
    • OTTHUMP00000025802
    • OTTMUSP00000019634
    • OTTMUSP00000019635
    • OTTMUSP00000019636
    • Putative RNA binding protein 3
    • Putative RNA-binding protein 3
    • Rbm3
    • RBM3_HUMAN
    • RNA binding motif (RNP1, RRM) protein 3
    • RNA binding motif protein 3
    • RNA-binding motif protein 3
    • RNA-binding protein 3
    • RNPL
    • RP23-27I6.7
    see all
  • Function
    Cold-inducible mRNA binding protein that enhances global protein synthesis at both physiological and mild hypothermic temperatures. Reduces the relative abundance of microRNAs, when overexpressed. Enhances phosphoryaltion of translation initiation factors and active polysome formation.
  • Sequence similarities
    Contains 1 RRM (RNA recognition motif) domain.
  • Post-translational
    modifications
    Arg-105 is dimethylated, probably to asymmetric dimethylarginine.
    Phosphorylated.
  • Cellular localization
    Nucleus. Cytoplasm. Cell projection > dendrite. Localizes in mRNA granules in dentrites.
  • Information by UniProt

Images

  • 12.5% SDS-PAGE analysis of ab116747 at approximately 34.43kDa, stained with Coomassie Blue.

References

ab116747 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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