Recombinant Human RBP4 protein (ab59967)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MERDCRVSSF RVKENFDKAR FSGTWYAMAK KDPEGLFLQD NIVAEFSVDE TGQMSATAKG RVRLLNNWDV CADMVGTFTD TEDPAKFKMK YWGVASFLQK GNDDHWIVDT DYDTYAVQYS CRLLNLDGTC ADSYSFVFSR DPNGLPPEAQ KIVRQRQEEL CLARQYRLIV HNGYCDGRSE RNLL
    • Amino acids
      19 to 201

Specifications

Our Abpromise guarantee covers the use of ab59967 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Form
    Liquid
  • Additional notes
    Endotoxin test showed more than 0.5 EU/mg endotoxin level.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: PBS, pH 7.4 (10mM Phosphate, 137mM NaCl, 2.7mM KCl)

General Info

  • Alternative names
    • OTTHUMP00000020114
    • OTTHUMP00000020115
    • OTTHUMP00000020116
    • Plasma retinol binding protein 4
    • Plasma retinol-binding protein
    • Plasma retinol-binding protein(1-176)
    • PRBP
    • PRO2222
    • RBP
    • RBP4
    • RDCCAS
    • RET4_HUMAN
    • Retinol binding protein 4
    • Retinol binding protein 4 interstitial
    • Retinol binding protein 4 plasma
    see all
  • Function
    Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.
  • Involvement in disease
    Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [MIM:180250]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium.
  • Sequence similarities
    Belongs to the calycin superfamily. Lipocalin family.
  • Cellular localization
    Secreted.
  • Information by UniProt

Images

  • ab59967 on 15% SDS-PAGE (3µg).

References

ab59967 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Thank you for your enquiry. This product contains protein in PBS buffer (10mM NaH2PO4, 137mM NaCl, 2.7mM KCl, pH7.4) and doesn’t include any other components such as BSA, sodium azide etc. However, as the result of endotoxin test this product showe...

Read More

Thank you for your enquiry. I can confirm that this product is sodium azide free. Furthermore, the buffer-composition of this product is 10mM Phosphate, 137mM NaCl, 2.7mM KCl, pH7.4 (PBS,pH7.4) and this product has no other constituent.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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