Recombinant Human REG1 alpha protein (ab63305)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceMKHHHHHHAS HMQEAQTELP QARISCPEGT NAYRSYCYYF NEDRETWVDA DLYCQNMNSG NLVSVLTQAE GAFVASLIKE SGTDDFNVWI GLHDPKKNRR WHWSSGSLVS YKSWGIGAPS SVNPGYCVSL TSSTGFQKWK DVPCEDKFSF VCKFKN

Associated products

Specifications

Our Abpromise guarantee covers the use of ab63305 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Western blot

    ELISA

  • Purity> 95 % SDS-PAGE.
    Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
  • FormLyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 5mM Tris, 25mM Sodium chloride, pH 7.5

  • ReconstitutionAdd deionized water to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely.

General Info

  • Alternative names
    • ICRF
    • Islet cells regeneration factor
    • Islet of Langerhans regenerating protein
    • Lithostathine
    • Lithostathine 1 alpha
    • Lithostathine 1 alpha precursor
    • Lithostathine-1-alpha
    • MGC12447
    • P19
    • Pancreatic stone protein
    • Pancreatic stone protein secretory
    • Pancreatic thread protein
    • Protein X
    • PSP
    • PSPS
    • PSPS1
    • PTP
    • RATRGPI
    • REG
    • REG-1-alpha
    • Reg1
    • REG1A
    • REG1A_HUMAN
    • Regenerating islet derived 1 alpha
    • Regenerating islet derived 1 alpha pancreatic stone protein pancreatic thread protein
    • Regenerating islet-derived protein 1-alpha
    • Regenerating protein I alpha
    see all
  • FunctionMight act as an inhibitor of spontaneous calcium carbonate precipitation. May be associated with neuronal sprouting in brain, and with brain and pancreas regeneration.
  • Tissue specificityIn pancreatic acinar cells and, in lower levels, in brain. Enhanced expression of PSP-related transcripts and intraneuronal accumulation of PSP-like proteins is found in brain from Alzheimer disease and Down syndrome patients.
  • Sequence similaritiesContains 1 C-type lectin domain.
  • Developmental stageHigh expression levels in fetal and infant brains; much lower in adult brains.
  • Post-translational
    modifications
    The composition of the O-linked carbohydrate on Thr-27 is complex and varied. In the crystallographic structure, the attached sugar appears to be N-acetylglucosamine, typical of an intracellular protein, rather than N-acetylgalactosamine.
  • Cellular localizationSecreted.
  • Information by UniProt

Recombinant Human REG1 alpha protein images

  • 1. MW marker – 14, 21, 31, 45, 66, 97 kDa
    2. reduced and heated sample, 2.5µg/lane
    3. non-reduced and non-heated sample, 2.5µg/lane

References for Recombinant Human REG1 alpha protein (ab63305)

ab63305 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab63305.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"