Recombinant Human REG1 alpha protein (ab73778)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceMKHHHHHHAS HMQEAQTELP QARISCPEGT NAYRSYCYYF NEDRETWVDA DLYCQNMNSG NLVSVLTQAE GAFVASLIKE SGTDDFNVWI GLHDPKKNRR WHWSSGSLVS YKSWGIGAPS SVNPGYCVSL TSSTGFQKWK DVPCEDKFSF VCKFKN
    • Molecular weight18 kDa
    • Additional sequence informationThe Recombinant Human REG 1 alpha is produced with N-terminal fusion His Tag.

Specifications

Our Abpromise guarantee covers the use of ab73778 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

    SDS-PAGE

  • Purity> 95 % SDS-PAGE.
    Sterile filtered.
  • FormLyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 5mM Tris, 25mM Sodium chloride, pH 7.5

  • ReconstitutionAdd 0.2 ml of deionized H2O and let the lyophilized pellet dissolve completely.

General Info

  • Alternative names
    • ICRF
    • Islet cells regeneration factor
    • Islet of Langerhans regenerating protein
    • Lithostathine
    • Lithostathine 1 alpha
    • Lithostathine 1 alpha precursor
    • Lithostathine-1-alpha
    • MGC12447
    • P19
    • Pancreatic stone protein
    • Pancreatic stone protein secretory
    • Pancreatic thread protein
    • Protein X
    • PSP
    • PSPS
    • PSPS1
    • PTP
    • RATRGPI
    • REG
    • REG-1-alpha
    • Reg1
    • REG1A
    • REG1A_HUMAN
    • Regenerating islet derived 1 alpha
    • Regenerating islet derived 1 alpha pancreatic stone protein pancreatic thread protein
    • Regenerating islet-derived protein 1-alpha
    • Regenerating protein I alpha
    see all
  • FunctionMight act as an inhibitor of spontaneous calcium carbonate precipitation. May be associated with neuronal sprouting in brain, and with brain and pancreas regeneration.
  • Tissue specificityIn pancreatic acinar cells and, in lower levels, in brain. Enhanced expression of PSP-related transcripts and intraneuronal accumulation of PSP-like proteins is found in brain from Alzheimer disease and Down syndrome patients.
  • Sequence similaritiesContains 1 C-type lectin domain.
  • Developmental stageHigh expression levels in fetal and infant brains; much lower in adult brains.
  • Post-translational
    modifications
    The composition of the O-linked carbohydrate on Thr-27 is complex and varied. In the crystallographic structure, the attached sugar appears to be N-acetylglucosamine, typical of an intracellular protein, rather than N-acetylgalactosamine.
  • Cellular localizationSecreted.
  • Information by UniProt

References for Recombinant Human REG1 alpha protein (ab73778)

ab73778 has not yet been referenced specifically in any publications.

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