Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceMKHHHHHHAS HMDIIMRPSC APGWFYHKSN CYGYFRKLRN WSDAELECQS YGNGAHLASI LSLKEASTIA EYISGYQRSQ PIWIGLHDPQ KRQQWQWIDG AMYLYRSWSG KSMGGNKHCA EMSSNNNFLT WSSNECNKRQ HFLCKYRP

Specifications

Our Abpromise guarantee covers the use of ab63304 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Western blot

    ELISA

  • Purity> 95 % SDS-PAGE.
    Please filter the product by an appropriate sterile filter before using it in the cell culture.
  • FormLyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 20mM Tris, pH 8

  • ReconstitutionAdd deionized water to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile!

General Info

  • Alternative names
    • Gastrointestinal secretory protein
    • GISP
    • Reg IV
    • REG like protein
    • REG-4
    • REG-like protein
    • Reg4
    • REG4_HUMAN
    • Regenerating gene type IV
    • Regenerating islet derived family member 4
    • Regenerating islet derived protein 4 precursor
    • Regenerating islet-derived protein 4
    • Regenerating islet-derived protein IV
    • REGIV
    • RELP
    see all
  • FunctionMay be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium.
  • Tissue specificityHighly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentially expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells.
  • Sequence similaritiesContains 1 C-type lectin domain.
  • Cellular localizationSecreted.
  • Information by UniProt

Recombinant Human REG4 protein images

  • 1. MW marker – 14, 21, 31, 45, 66, 97 kDa
    2. reduced and heated sample, 5µg/lane
    3. non-reduced and non-heated sample, 5µg/lane

References for Recombinant Human REG4 protein (ab63304)

ab63304 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"