Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MKHHHHHHAS HMDIIMRPSC APGWFYHKSN CYGYFRKLRN WSDAELECQS YGNGAHLASI LSLKEASTIA EYISGYQRSQ PIWIGLHDPQ KRQQWQWIDG AMYLYRSWSG KSMGGNKHCA EMSSNNNFLT WSSNECNKRQ HFLCKYRP
    • Molecular weight
      17 kDa
    • Tags
      His tag N-Terminus
    • Additional sequence information
      The Recombinant Human REG-4 is manufactured with N-terminal fusion of His Tag.

Specifications

Our Abpromise guarantee covers the use of ab73781 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

    SDS-PAGE

  • Purity
    > 95 % SDS-PAGE.

  • Form
    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20mM Tris, pH 8.0

  • Reconstitution
    Add 0.2 ml of deionized H2O and let the lyophilized pellet dissolve completely.

General Info

  • Alternative names
    • Gastrointestinal secretory protein
    • GISP
    • Reg IV
    • REG like protein
    • REG-4
    • REG-like protein
    • Reg4
    • REG4_HUMAN
    • Regenerating gene type IV
    • Regenerating islet derived family member 4
    • Regenerating islet derived protein 4 precursor
    • Regenerating islet-derived protein 4
    • Regenerating islet-derived protein IV
    • REGIV
    • RELP
    see all
  • Function
    May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium.
  • Tissue specificity
    Highly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentially expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells.
  • Sequence similarities
    Contains 1 C-type lectin domain.
  • Cellular localization
    Secreted.
  • Information by UniProt

References

ab73781 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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