Recombinant Human Relaxin 3 protein (ab50135)

Overview

  • Product nameRecombinant Human Relaxin 3 protein
  • Protein lengthProtein fragment

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceA-chain -DVLAGLSSS CCKWGCSKSE ISSLC B-chain -RAAPYGVRL CGREFIRAVI FTCGGSRW

Specifications

Our Abpromise guarantee covers the use of ab50135 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Endotoxin level< 0.100 Eu/µg
  • Purity> 95 % SDS-PAGE.
    Purity: greater than 98% by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng per µg (1EU/µg).
  • FormLyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

  • ReconstitutionCentrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4oC for 1 week or -20oC for future use.

General Info

  • Alternative names
    • H3
    • INSL 7
    • INSL7
    • Insulin like 7
    • Insulin like peptide 7
    • Insulin like peptide INSL7
    • Insulin like7
    • Insulinlike 7
    • Prorelaxin H3
    • Prorelaxin M3
    • REL 3
    • REL3
    • Relaxin 3
    • Relaxin 3 (H3)
    • Relaxin 3 A chain
    • Relaxin 3 B chain
    • Relaxin 3 precursor
    • Relaxin3
    • RLN 3
    • RLN3
    • RXN 3
    • RXN3
    • ZINS 4
    • ZINS4
    see all
  • RelevanceRelaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. The protein encoded by this gene is a member of the relaxin family. The active form of the encoded protein consists of an A chain and a B chain but their cleavage sites are not definitely described yet. It may play a role in neuropeptide signaling processes.
  • Cellular localizationSecreted

References for Recombinant Human Relaxin 3 protein (ab50135)

ab50135 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting Abcam regarding ab50135.


We recommend storing the lyophilised material at -20oC to -80oC, as this is its most stable form. It can be stored this way for up to 1 year after receipt.


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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"