Recombinant Human Ribonuclease Inhibitor protein (ab114503)

Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MSLDIQSLDIQCEELSDARWAELLPLLQQCQVVRLDDCGLTEARCKDISS ALRVNPALAELNLRSNELGDVGVHCVLQGLQTPSCKIQKLSLQNCCLTGA GCGVLSSTLRTLPTLQELHLSDNLLGDAGLQLLCEGLLDPQCRLEKLQLE YCSLSAASCEPLASVLRAKPDFKELTVSNNDINEAGVRVLCQGLKDSPCQ LEALKLESCGVTSDNCRDLCGIVASKASLRELALGSNKLGDVGMAELCPG LLHPSSRLRTLWIWECGITAKGCGDLCRVLRAKESLKELSLAGNELGDEG ARLLCETLLEPGCQLESLWVKSCSFTAACCSHFSSVLAQNRFLLELQISN NRLEDAGVRELCQGLGQPGSVLRVLWLADCDVSDSSCSSLAATLLANHSL RELDLSNNCLGDAGILQLVESVRQPGCLLEQLVLYDIYWSEEMEDRLQAL EKDKPSLRVIS
    • Molecular weight
      76 kDa including tags
    • Amino acids
      1 to 461

Associated products

Specifications

Our Abpromise guarantee covers the use of ab114503 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml. This protein is best used within three months from the date of receipt.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris-HCl buffer

General Info

  • Alternative names
    • AW546468
    • C80305
    • MGC18200
    • MGC4569
    • MGC54054
    • OTTHUMP00000147628
    • OTTHUMP00000229864
    • OTTHUMP00000229865
    • OTTHUMP00000229866
    • OTTHUMP00000229870
    • OTTHUMP00000229871
    • OTTHUMP00000229872
    • Placental ribonuclease inhibitor
    • Placental RNase inhibitor
    • PRI
    • RAI
    • RI
    • Ribonuclease inhibitor
    • Ribonuclease/angiogenin inhibitor
    • Ribonuclease/angiogenin inhibitor 1
    • RINI_HUMAN
    • RNase inhibitor
    • RNH
    • RNH 1
    • RNH1
    • Rnh1 ribonuclease/angiogenin inhibitor 1
    see all
  • Function
    Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play role in redox homeostasis.
  • Sequence similarities
    Contains 15 LRR (leucine-rich) repeats.
  • Domain
    The LRR domain forms a horseshoe-shaped structure that interacts tightly with target RNAses via a large protein interaction surface on its interior side.
  • Post-translational
    modifications
    The N-terminus is blocked.
    At least 30 of the 32 cysteine residues are in the reduced form.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt

Images

  • ab114503 analysed by 12.5% SDS-PAGE and stained with Coomassie Blue.

References

ab114503 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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