Overview

Description

  • NatureRecombinant
  • SourceBaculovirus infected Sf9 cells
  • Amino Acid Sequence
    • SpeciesHuman

Associated products

Specifications

Our Abpromise guarantee covers the use of ab89694 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityThe Specific activity of ab89694 was determined to be 6 nmol/min/mg.
  • Applications

    Western blot

    Functional Studies

  • FormLiquid
  • Additional notes

    ab64311 (Myelin Basic Protein protein) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • DSTYK
    • Dual serine/threonine and tyrosine protein kinase
    • Dusty PK
    • Dusty protein kinase
    • DUSTY_HUMAN
    • HDCMD38P
    • KIAA0472
    • Receptor interacting protein 5
    • Receptor interacting protein kinase 5
    • Receptor interacting serine/threonine protein kinase 5
    • Receptor-interacting serine/threonine-protein kinase 5
    • RIP homologous kinase
    • RIP-homologous kinase
    • RIP5
    • RIPK5
    • SgK496
    • Sugen kinase 496
    see all
  • FunctionMay induce both caspase-dependent apoptosis and caspase-independent cell death.
  • Tissue specificityPredominantly expressed in skeletal muscle and testis. Weakly expressed in heart, brain, placenta, kidney, pancreas, spleen, thymus, prostate, uterus, small intestine, white blood cells, stomach, spinal cord and adrenal gland. Is widely distributed in the CNS. Also detected in several tumor cell lines.
  • Sequence similaritiesBelongs to the protein kinase superfamily. Ser/Thr protein kinase family.
    Contains 1 protein kinase domain.
  • Cellular localizationCytoplasm.
  • Information by UniProt

Recombinant human RIPK5 protein images

  • SDS-PAGE showing ab89694 at approximately 140kDa.
  • Kinase Assay demonstrating specific activity of ab89694.

References for Recombinant human RIPK5 protein (ab89694)

ab89694 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"