Overview

  • Product nameRecombinant Human RND1 protein
  • Protein lengthFull length protein

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionQ92730
    • SpeciesHuman
    • SequenceMGSSHHHHHH SSGLVPRGSH SPYYDNVRPL CYSDSDAVLL CFDISRPETV DSALKKWRTE ILDYCPSTRV LLIGCKTDLR TDLSTLMELS HQKQAPISYE QGCAIAKQLG MKERRAPQPV VARCKLVLVG DVQCGKTAML QVLAKDCYPE TYVPTVFENY TACLETEEQR VELSLWDTSG AEIYLEGSAF TSEKSIHSIF RTASMLCLNK PSPLPQKSPV
    • Molecular weight25 kDa
    • Amino acids1 to 200
    • TagsHis tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab109840 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF
  • Purity> 95 % SDS-PAGE.
    No detergents such as urea, Triton or Tween were used to purify the proteins. Purified by using anion exchange chromatography (DEAE sepharose resin) and gel filtration chromatography (Sephacryl S 200) with 20mM Tris pH 7.5, 2mM EDTA.
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 30% Glycerol, 0.58% Sodium chloride, 0.02% DTT

General Info

  • Alternative names
    • ARHS
    • FLJ42294
    • GTP binding protein RHO6
    • Ras homolog gene family member S
    • RHO 6
    • Rho family GTPase 1
    • Rho related GTP binding protein Rho6
    • RHO S
    • Rho-related GTP-binding protein Rho6
    • RHO6
    • RHOS
    • RND 1
    • Rnd1
    • RND1_HUMAN
    see all
  • FunctionLacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments.
  • Tissue specificityMostly expressed in brain and liver.
  • Sequence similaritiesBelongs to the small GTPase superfamily. Rho family.
  • Cellular localizationCell membrane. Cytoplasm > cytoskeleton.
  • Information by UniProt

Recombinant Human RND1 protein images

  • SDS-PAGE analysis of ab109840: (1) MW marker, (2) ab109840 at 3µg
    Gel concentration: 15%

References for Recombinant Human RND1 protein (ab109840)

This product has been referenced in:
  • Nobes CD  et al. A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion. J Cell Biol 141:187-97 (1998). Read more (PubMed: 9531558) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"