Overview

Description

  • NatureRecombinant
  • SourceWheat germ
  • Amino Acid Sequence
    • AccessionP39019
    • SpeciesHuman
    • SequenceAPYDENWFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSRG SKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKKH
    • Molecular weight37 kDa including tags
    • Amino acids46 to 145

Associated products

Specifications

Our Abpromise guarantee covers the use of ab114627 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • FormLiquid
  • Additional notesProtein concentration is above or equal to 0.05 mg/ml. This protein is best used within three months from the date of receipt.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • 40S ribosomal protein S19
    • DBA
    • DBA1
    • HGNC:10402
    • Ribosomal protein S19
    • rps19
    • RS19_HUMAN
    • S19
    see all
  • FunctionRequired for pre-rRNA processing and maturation of 40S ribosomal subunits.
  • Tissue specificityHigher level expression is seen in the colon carcinoma tissue than normal colon tissue.
  • Involvement in diseaseDefects in RPS19 are the cause of Diamond-Blackfan anemia type 1 (DBA1) [MIM:105650]. DBA1 is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies.
  • Sequence similaritiesBelongs to the ribosomal protein S19e family.
  • Cellular localizationNucleus. Located more specifically in the nucleoli.
  • Information by UniProt

Recombinant Human RPS19 protein images

  • ab114627 analysed by 12.5% SDS-PAGE and stained with Coomassie Blue.

References for Recombinant Human RPS19 protein (ab114627)

ab114627 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"