Recombinant Human RRAS2 protein (ab90741)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human

Associated products

Specifications

Our Abpromise guarantee covers the use of ab90741 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 95 % SDS-PAGE.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 5mM Magnesium chloride, 5mM Beta mercaptoethanol, 25mM Tris HCl, 150mM Sodium chloride, pH 7.5

General Info

  • Alternative names
    • C86394
    • Oncogene RRAS2
    • Oncogene TC21
    • Ras like protein TC21
    • Ras related protein R Ras2
    • Ras-like protein TC21
    • Ras-related protein R-Ras2
    • Related RAS viral (r ras) oncogene homolog 2
    • Related RAS viral oncogene homolog 2
    • RRAS 2
    • RRAS2
    • RRAS2_HUMAN
    • TC 21
    • TC21
    • Teratocarcinoma oncogene
    • Teratocarcinoma oncogene TC21
    see all
  • Function
    It is a plasma membrane-associated GTP-binding protein with GTPase activity. Might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins but in an antagonistic fashion.
  • Tissue specificity
    Ubiquitously present in all tissues examined, with the highest levels in heart, placenta, and skeletal muscle. Moderate levels in lung and liver; low levels in brain, kidney, and pancreas.
  • Involvement in disease
    Ovarian cancer
  • Sequence similarities
    Belongs to the small GTPase superfamily. Ras family.
  • Post-translational
    modifications
    May be post-translationally modified by both palmitoylation and polyisoprenylation.
  • Cellular localization
    Cell membrane. Inner surface of plasma membrane possibly with attachment requiring acylation of the C-terminal cysteine (By similarity with RAS).
  • Information by UniProt

References

ab90741 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Te confirmo que la proteína RRAS2 (Tagged) también tiene GST como tag.

No dudes en consultarnos cualquier otra duda.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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