Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Species
      Human

Specifications

Our Abpromise guarantee covers the use of ab60880 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Functional Studies

  • Form
    Liquid
  • Additional notes

    ab204880 (RPS6 peptide) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • 90 kDa ribosomal protein S6 kinase 1
    • dJ590P13.1
    • dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1
    • EC 2.7.11.1
    • HU 1
    • HU1
    • KS6A1_HUMAN
    • MAP kinase activated protein kinase 1a
    • MAP kinase-activated protein kinase 1a
    • MAPK-activated protein kinase 1a
    • MAPKAP kinase 1a
    • MAPKAPK-1a
    • MAPKAPK1A
    • MGC79981
    • Mitogen-activated protein kinase-activated protein kinase 1A
    • OTTHUMP00000004113
    • p90 RSK1
    • p90-RSK 1
    • p90rsk
    • p90RSK1
    • p90S6K
    • pp90RSK1
    • Ribosomal protein S6 kinase 90kD 1
    • Ribosomal protein S6 kinase 90kD polypeptide 1
    • Ribosomal protein S6 kinase 90kDa polypeptide 1
    • Ribosomal protein S6 kinase alpha 1
    • Ribosomal protein S6 kinase alpha-1
    • Ribosomal protein S6 kinase polypeptide 1
    • Ribosomal S6 kinase 1
    • RPS6K1 alpha
    • rps6ka
    • Rps6ka1
    • RSK
    • RSK 1
    • RSK 1 p90
    • RSK-1
    • RSK1
    • S6K alpha 1
    • S6K-alpha-1
    see all
  • Function
    Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.
  • Sequence similarities
    Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 2 protein kinase domains.
  • Post-translational
    modifications
    Autophosphorylated on Ser-380, as part of the activation process.
  • Information by UniProt

Images

  • Sample Kinase Activity Plot.
  • ab60880 on SDS-PAGE, MW ~108 kDa.

References

This product has been referenced in:

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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