Overview

Description

  • NatureRecombinant
  • SourceBaculovirus infected Sf9 cells
  • Amino Acid Sequence
    • SpeciesHuman

Specifications

Our Abpromise guarantee covers the use of ab85296 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activitySpecific activity: 540nmol/min/mg.
  • Applications

    Western blot

    Functional Studies

  • FormLiquid
  • Additional notes

    ab204879 (RPS6 peptide) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • 90 kDa ribosomal protein S6 kinase 6
    • KS6A6_HUMAN
    • p90 RSK 6
    • p90-RSK 6
    • p90RSK6
    • pp90RSK4
    • Ribosomal protein S6 kinase 90kDa polypeptide 6
    • Ribosomal protein S6 kinase alpha 6
    • Ribosomal protein S6 kinase alpha-6
    • Ribosomal S6 kinase 4
    • rps6ka6
    • RSK 4
    • RSK-4
    • S6K-alpha-6
    see all
  • FunctionSerine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.
  • Sequence similaritiesBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 2 protein kinase domains.
  • Post-translational
    modifications
    Autophosphorylated on Ser-389, as part of the activation process.
  • Information by UniProt

Recombinant human RSK4 protein images

  • Example of specific activity of ab85296
  • SDS Page analysis of ab85296

References for Recombinant human RSK4 protein (ab85296)

ab85296 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"