FunctionMay function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes. May also play a role in suppressing tumor cell growth.
Tissue specificityA subset of epithelial cells including normal human mammary epithelial cells and keratinocytes.
Sequence similaritiesBelongs to the S-100 family. Contains 2 EF-hand domains.
Developmental stagePreferentially expressed in normal human mammary epithelial cells as opposed to tumor-derived ones. The level of S100L was shown to correlate inversely with tumor progression.