FunctionMay function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative.
Sequence similaritiesBelongs to the S-100 family. Contains 2 EF-hand domains.
Post-translational modificationsThe N-terminus is blocked.
15% SDS-PAGE showing ab104645 at approximately 12.3kDa (3µg).
References for Recombinant Human S100 alpha 6 protein (ab104645)
This product has been referenced in:
Lorenzi R et al. Soluble form of receptor for advanced glycation end-products (sRAGE): do sRAGE ligands or anti-sRAGE auto-antibodies interfere with sRAGE quantification? Ann Clin BiochemN/A:N/A (2013).
Read more (PubMed: 23982266) »