Additional sequence informationS100A1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 103 amino acids which include a 10 amino acid His Tag fused at N-terminus.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
S-100 protein alpha chain
S-100 protein subunit alpha
S100 Calcium Binding Protein A1
S100 calcium-binding protein A1
S100 protein alpha polypeptide
FunctionWeakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites.
Tissue specificityHighly prevalent in heart. Also found in lesser quantities in skeletal muscle and brain.
Sequence similaritiesBelongs to the S-100 family. Contains 2 EF-hand domains.