The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 µg/µl.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
bA291O7.3 discs large Drosophila homolog 3 neuroendocrine dlg
Discs large Drosophila homolog 3
Discs large homolog 3
Discs large homolog 3 neuroendocrine dlg Drosophila
Discs large homolog 3 Drosophila
Discs, large homolog 3 (Drosophila)
Disks large homolog 3
Synapse associated protein 102
Synapse-associated protein 102
Required for learning most likely through its role in synaptic plasticity following NMDA receptor signaling.
Involvement in disease
Defects in DLG3 are the cause of mental retardation X-linked type 90 (MRX90) [MIM:300189]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.
Belongs to the MAGUK family. Contains 1 guanylate kinase-like domain. Contains 3 PDZ (DHR) domains. Contains 1 SH3 domain.