The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
30 kDa Sin3-associated polypeptide
Histone deacetylase complex subunit SAP 30
Histone deacetylase complex subunit SAP30
MSin3A associated polypeptide p30
Sin3 associated polypeptide
Sin3 associated polypeptide 30 kDa
Sin3 associated polypeptide 30kD
Sin3 corepressor complex subunit SAP 30
Sin3 corepressor complex subunit SAP30
Sin3-associated polypeptide p30
Sin3A associated protein
Sin3A associated protein 30kDa
Involved in the functional recruitment of the Sin3-histone deacetylase complex (HDAC) to a specific subset of N-CoR corepressor complexes. Capable of transcription repression by N-CoR. Active in deacetylating core histone octamers (when in a complex) but inactive in deacetylating nucleosomal histones.
Expressed in all tissues tested with highest levels in pancreas, ovary, PBL, spleen and thymus; lowest levels in brain, placenta, lung and kidney.