The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
% SDS-PAGE. ab117173 is purified by proprietary chromatographic techniques.
Additional notesAlthough stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Please see notes section.
pH: 8.00 Constituents: 0.32% Tris HCl, 10% Glycerol
Diamine acetyltransferase 1
Diamine N acetyltransferase 1
Polyamine N acetyltransferase 1
Polyamine N-acetyltransferase 1
Spermidine/spermine N(1) acetyltransferase 1
Spermidine/spermine N(1)-acetyltransferase 1
Spermidine/spermine N1 acetyltransferase 1
Spermidine/spermine N1 acetyltransferase alpha
FunctionEnzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine = spermidine >> spermine > N(1)-acetylspermine > putrescine. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Also involved in the regulation of polyamine transport out of cells. Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)-acetylspermidine and N(8)-acetylspermidine.
PathwayAmine and polyamine degradation; putrescine degradation; N-acetylputrescine from putrescine: step 1/1.
Involvement in diseaseKeratosis follicularis spinulosa decalvans X-linked
Sequence similaritiesBelongs to the acetyltransferase family. Contains 1 N-acetyltransferase domain.