Recombinant Human SCC112 protein (ab161580)
Key features and details
- Expression system: Wheat germ
- Tags: GST tag N-Terminus
- Suitable for: ELISA, WB
Description
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Product name
Recombinant Human SCC112 protein -
Expression system
Wheat germ -
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MIHLLAHDPDFTRSQDVDQLRDIKECLWFMLEVLMTKNENNSHAFMKKMA ENIKLTRDAQSPDESKTNEKLYTVCDVALCVINSKSALCNADSPKDPVLP MKFFTQPEKDFCNDKSYISEETRVLLLTGKPKPAGVLGAVNKPLSATGRK PYVRSTGTETGSNINVNSELNPSTGNRSREQSSEAAETGVSENEENPVRI ISVTPVKNIDPVKNKEINSDQATQGNISSDRGKKRTVTAAGAENIQQKTD EKVDESGPPAPSKPRRGRRPKSESQGNATKNDDLNKPINKGRKRAAVGQE SPGGLEAGNAKAPKLQDLAKKAAPAERQIDLQR -
Amino acids
1 to 333 -
Tags
GST tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab161580 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
ELISA
Western blot
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Form
Liquid -
Additional notes
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- Cell proliferation inducing protein 54
- Cell proliferation-inducing gene 54 protein
- KIAA0648
see all -
Function
Probable regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. -
Tissue specificity
Highest level in colon. Low levels in lung, ovary, breast and kidney. Reduced level in renal tumor tissue. Isoform 2 is expressed in kidney. -
Sequence similarities
Belongs to the PDS5 family.
Contains 1 HEAT repeat. -
Developmental stage
Cell cycle-regulated with highest level in G2 phase. -
Cellular localization
Nucleus. Associated with chromatin through most of the cell cycle. Dissociates from chromatin in late prophase, reassociates during late telophase. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab161580 has not yet been referenced specifically in any publications.