Recombinant Human SCGF beta protein (ab54178)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman

Associated products

Specifications

Our Abpromise guarantee covers the use of ab54178 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 95 % SDS-PAGE.
    Purity: 98 % (SDS-PAGE, HPLC) Endotoxin level: < 0.1 ng per ug of SCGF beta
  • FormLyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 0.5 x PBS, pH 7.3

  • ReconstitutionThe lyophilized SCGF beta is soluble in water and most aqueous buffers. The lyophilized protein should be reconstituted in water to a concentration of 0.1 - 1.0 mg/ml. It is recommended that further dilutions be made into buffer containing carrier protein or medium containing serum.

General Info

  • Alternative names
    • C type lectin domain family 11 member A
    • C type lectin superfamily member 3
    • C-type lectin domain family 11 member A
    • C-type lectin superfamily member 3
    • CLC11_HUMAN
    • CLEC11A
    • CLECSF3
    • LSLCL
    • Lymphocyte secreted C type lectin
    • Lymphocyte secreted C-type lectin
    • p47
    • Stem cell growth factor
    see all
  • FunctionStimulates the proliferation and differentiation of hematopoietic precursor cells from various lineages, including erythrocytes, lymphocytes, granulocytes and macrophages. Acts synergistically with other cytokines, including IL-3, GCSF, GMCSF and FLT3 ligand. Suppresses SCF-stimulated erythrocyte proliferation.
  • Tissue specificityExpressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver.
  • Sequence similaritiesContains 1 C-type lectin domain.
  • Developmental stageIn the bone marrow, expression is limited to immature neutrophils. Expression was not detected in circulating mature neutrophils.
  • Post-translational
    modifications
    O-glycosylated. Probably sulfated on the O-glycans.
  • Cellular localizationCytoplasm. Secreted.
  • Information by UniProt

References for Recombinant Human SCGF beta protein (ab54178)

ab54178 has not yet been referenced specifically in any publications.

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