Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHHSSGLVPRGSHMGSMSTGLRYKSKLATPEDKQDIDKQYVGF ATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLS AEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITD YVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKA LHEKVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDE DEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAH CDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSKLTQDSRMES PIPILPLPTPDAETEKLIRMKDEELRRMQEMLQRMKQQMQDQ
    • Molecular weight
      45 kDa including tags
    • Amino acids
      1 to 369
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab109972 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF
  • Purity
    > 90 % SDS-PAGE.
    ab109972 was purified using conventional chromatography.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 40% Glycerol, 0.3M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0

General Info

  • Alternative names
    • 5 Sep
    • CDCREL
    • CDCrel 1
    • CDCrel-1
    • CDCREL1
    • Cell division control related protein 1
    • Cell division control-related protein 1
    • H5
    • HCDCREL 1
    • OTTHUMP00000197271
    • OTTHUMP00000197272
    • OTTHUMP00000197273
    • OTTHUMP00000197274
    • OTTHUMP00000197275
    • OTTHUMP00000197276
    • OTTHUMP00000197396
    • OTTHUMP00000197410
    • Peanut like 1
    • Peanut like 1 homolog
    • Peanut like protein 1
    • Peanut-like protein 1
    • Platelet glycoprotein Ib beta chain
    • PNUTL1
    • SEPT5
    • SEPT5_HUMAN
    • Septin 5
    • Septin-5
    see all
  • Function
    Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion.
  • Tissue specificity
    Expressed at high levels in the CNS, as well as in heart and platelets (at protein level).
  • Sequence similarities
    Belongs to the septin family.
  • Post-translational
    modifications
    In platelets, phosphorylated in response to thrombin, phorbol-12-myristate-13-acetate and collagen.
  • Cellular localization
    Cytoplasm. Cytoplasm > cytoskeleton. In platelets, found in areas surrounding alpha-granules.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of 3 µg ab109972.

References

ab109972 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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