Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MDDPSVGPKIPQALEKILQLKESRQEEMNSQQEEEEMETDARSSLGQSAS ETEEDTVSVSKKEKNRKRRNRKKKKKPQRVRGVSSESSGDREKDSTRSRG SDSPAADVEIEYVTEEPEIYEPNFIFFKRIFEAFKLTDDVKKEKEKEPEK LDKLENSAAPKKKGFEEEHKDSDDDSSDDEQEKKPEAPKLSKKKLRRMNR FTVAELKQLVARPDVVEMHDVTAQDPKLLVHLKATRNSVPVPRHWCFKRK YLQGKRGIEKPPFELPDFIKRTGIQEMREALQEKEEQKTMKSKMREKVRP KMGKIDIDYQKLHDAFFKWQTKPKLTIHGDLYYEGKEFETRLKEKKPGDL SDELRISLGMPVGPNAHKVPPPWLIAMQRYGPPPSYPNLKIPGLNSPIPE SCSFGYHAGGWGKPPVDETGKPLYGDVFGTNAAEFQTKTEEEEIDRTPWG ELEPSDEESSEEEEEEESDEDKPDETGFITPADSGLITPGGFSSVPAGME TPELIELRKKKIEEAMDGSETPQLFTVLPEKRTATVGGAMMGSTHIYDMS TVMSRKGPAPELQGVEVALAPEELELDPMAMTQKYEEHVREQQAQVEKED FSDMVAEHAAKQKQKKRKAQPQDSRGGSKKYKEFKF
    • Amino acids
      1 to 636
    • Tags
      proprietary tag N-Terminus

Associated products

Specifications

Our Abpromise guarantee covers the use of ab161228 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • Pre mRNA splicing factor SF3b 145 kDa subunit
    • SAP 145
    • SAP145
    • SF3b1
    • SF3B145
    • SF3b150
    • Spliceosome associated protein 145
    • Splicing factor 3b subunit 2
    • Splicing factor 3b subunit 2 145kDa
    see all
  • Relevance
    SF3B2 is a subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. SF3B2 may also be involved in the assembly of the 'E' complex. It also belongs to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
  • Cellular localization
    Nuclear

Images

  • ab161228 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab161228 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab161228.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up