Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Species
      Human

Associated products

Specifications

Our Abpromise guarantee covers the use of ab55673 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    Specific Activity: 78nmol/min/mg
  • Applications

    SDS-PAGE

    Functional Studies

  • Form
    Liquid
  • Additional notes

    ab204849 (AKT1 peptide) can be utilized as a substrate for assessing kinase activity

     

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • CISK
    • Cytokine independent survival kinase
    • DKFZp781N0293
    • Serine/threonine protein kinase Sgk3
    • Serine/threonine-protein kinase Sgk3
    • Serum/glucocorticoid regulated kinase 3
    • Serum/glucocorticoid regulated kinase family member 3
    • Serum/glucocorticoid regulated kinase like
    • Serum/glucocorticoid-regulated kinase 3
    • Serum/glucocorticoid-regulated kinase-like
    • SGK 2
    • SGK 3
    • SGK2
    • Sgk3
    • SGK3_HUMAN
    • SGKL
    see all
  • Function
    Involved in the activation of potassium channels. Mediates cell IL-3-dependent survival signals.
  • Tissue specificity
    Expressed in most tissues with highest levels in pancreas, kidney liver, heart and brain and lower levels in lung, placenta and skeletal muscle.
  • Sequence similarities
    Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 1 protein kinase domain.
    Contains 1 PX (phox homology) domain.
  • Cellular localization
    Cytoplasmic vesicle. Early endosome. Localized in vesicle-like structures and in the early endosome.
  • Information by UniProt

Images

  • SDS Page analysis of ab55673

References

ab55673 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab55673.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up