The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesProtein concentration is above or equal to 0.05 mg/ml. This protein is best used within three months from the date of receipt.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.3% Glutathione, 0.79% Tris HCl
Low affinity sodium glucose cotransporter
Low affinity sodium-glucose cotransporter
Na(+) glucose cotransporter 2
Na(+)/glucose cotransporter 2
Sodium glucose cotransporter 2
Sodium/glucose cotransporter 2
Solute carrier family 5 (sodium glucose cotransporter) member 2
Solute carrier family 5 (sodium/glucose transporter), member 2
Solute carrier family 5 member 2
FunctionSodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules.
Involvement in diseaseDefects in SLC5A2 are the cause of renal glucosuria (GLYS1) [MIM:233100]. GLYS1 is an autosomal recessive disorder characterized by a normal fasting serum glucose concentration and persistent isolated glucosuria, with a normal glucose tolerance test.
Sequence similaritiesBelongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.