The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml. This protein is best used within three months from the date of receipt.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.3% Glutathione, 0.79% Tris HCl
Low affinity sodium glucose cotransporter
Low affinity sodium-glucose cotransporter
Na(+) glucose cotransporter 2
Na(+)/glucose cotransporter 2
Sodium glucose cotransporter 2
Sodium/glucose cotransporter 2
Solute carrier family 5 (sodium glucose cotransporter) member 2
Solute carrier family 5 (sodium/glucose transporter), member 2
Solute carrier family 5 member 2
Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules.
Involvement in disease
Defects in SLC5A2 are the cause of renal glucosuria (GLYS1) [MIM:233100]. GLYS1 is an autosomal recessive disorder characterized by a normal fasting serum glucose concentration and persistent isolated glucosuria, with a normal glucose tolerance test.
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.