The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml. Best used within three months from the date of receipt.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.3% Glutathione, 0.79% Tris HCl
Mitochondrial phosphate carrier protein
Phosphate carrier protein
Phosphate carrier protein mitochondrial
Phosphate carrier protein mitochondrial precursor
Phosphate transport protein
Solute carrier family 25 member 3
Solute carrier family 25 mitochondrial carrier phosphate carrier member 3
Transport of phosphate groups from the cytosol to the mitochondrial matrix. Phosphate is cotransported with H(+).
Involvement in disease
Defects in SLC25A3 are a cause of mitochondrial phosphate carrier deficiency (MPCD) [MIM:610773]. MPCD is a fatal disorder of oxidative phosphorylation. Patients have lactic acidosis, hypertrophic cardiomyopathy and muscular hypotonia and die within the first year of life.
Belongs to the mitochondrial carrier family. Contains 3 Solcar repeats.