The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesProtein concentration is above or equal to 0.05 mg/ml
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.3% Glutathione, 0.79% Tris HCl
Neural crest transcription factor Slug
Protein snail homolog 2
Slug (chicken homolog) zinc finger protein
Slug homolog zinc finger protein
Slug zinc finger protein
Snail homolog 2
Zinc finger protein SLUG
Zinc finger protein SNAI2
FunctionTranscriptional repressor. Involved in the generation and migration of neural crest cells.
Tissue specificityExpressed in placenta and adult heart, pancreas, liver, kidney and skeletal muscle.
Involvement in diseaseDefects in SNAI2 are the cause of Waardenburg syndrome type 2D (WS2D) [MIM:608890]. WS2 is a genetically heterogeneous, autosomal dominant disorder characterized by sensorineural deafness, pigmentary disturbances, and absence of dystopia canthorum. The frequency of deafness is higher in WS2 than in WS1.
Sequence similaritiesBelongs to the snail C2H2-type zinc-finger protein family. Contains 5 C2H2-type zinc fingers.