Overview

  • Product nameRecombinant Human SNAPIN protein
  • Protein lengthFull length protein

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceMGSSHHHHHH SSGLVPRGSH MAGAGSAAVS GAGTPVAGPT GRDLFAEGLL EFLRPAVQQL DSHVHAVRES QVELREQIDN LATELCRINE DQKVALDLDP YVKKLLNARR RVVLVNNILQ NAQERLRRLN HSVAKETARR RAMLDSGIYP PGSPGK

Specifications

Our Abpromise guarantee covers the use of ab81766 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 90 % SDS-PAGE.
    ab81766 is purified using conventional chromatography techniques.
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 40% Glycerol, 0.2M Sodium chloride, 5mM DTT, 20mM Tris HCl, 2mM EDTA, pH 8.0

General Info

  • Alternative names
    • OTTHUMP00000035157
    • SNAP associated protein
    • SNAP-25-binding protein
    • SNAP-associated protein
    • SNAP25BP
    • SNAPAP
    • Snapin
    • SNAPN_HUMAN
    • SNARE associated protein snapin
    • SNARE-associated protein Snapin
    • Synaptosomal associated protein 25 binding protein
    • Synaptosomal-associated protein 25-binding protein
    see all
  • FunctionMay modulate a step between vesicle priming, fusion and calcium-dependent neurotransmitter release by potentiating the interaction of synaptotagmins with the SNAREs and the plasma-membrane-associated protein SNAP25. Its phosphorylation state influences exocytotic protein interactions and may regulate synaptic vesicle exocytosis. May also have a role in the mechanisms of SNARE-mediated membrane fusion in non-neuronal cells.
  • Tissue specificityExpressed in male germ cells of adult testis (at protein level).
  • Sequence similaritiesBelongs to the SNAPIN family.
  • Developmental stageExpressed in germ cells of 22-week prenatal testis.
  • Cellular localizationCytoplasm. Membrane. Cytoplasmic vesicle membrane. Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Cell junction > synapse > synaptosome. Cytoplasm > perinuclear region. May be cytoplasmic and peripheral membrane bound or anchored to the vesicular membrane through an N-terminal signal anchor (By similarity). Co-localizes with NANOS1 and PUM2 in the perinuclear region of germ cells.
  • Information by UniProt

Recombinant Human SNAPIN protein images

  • ab81766 on 15% SDS-PAGE (3µg)

References for Recombinant Human SNAPIN protein (ab81766)

ab81766 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab81766.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"