Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human
    • Additional sequence information
      Fused to a hexahistidine purification tag.

Specifications

Our Abpromise guarantee covers the use of ab70109 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Western blot

    ELISA

  • Purity
    > 90 % SDS-PAGE.
    Purity is greater than 90.0% as determined by RP-HPLC and SDS-PAGE.
  • Form
    Liquid
  • Additional notes


    This protein binds IgG-type human auto-antibodies.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 0.02% SDS, 20mM HEPES, 0.01mM EDTA, pH 7.5

General Info

  • Alternative names
    • RNPU1Z
    • Rnulp70
    • RPU1
    • Small nuclear ribonucleoprotein 70 (U1)
    • Small nuclear ribonucleoprotein 70kD polypeptide (RNP antigen)
    • Small nuclear ribonucleoprotein 70kDa (U1)
    • Small nuclear ribonucleoprotein 70kDa polypeptide (RNP antigen)
    • snRNP70
    • Snrp 70
    • SNRP70
    • U1 70K
    • U1 small nuclear ribonucleoprotein 70 kDa
    • U1 small nuclear ribonucleoprotein polypeptide A
    • U1 snRNP 70 kDa
    • U170K
    • U1AP
    • U1AP1
    • U1RNP
    see all
  • Relevance
    SNRP70 is an RNA-binding protein that is a specific component of the U1 small nuclear ribonucleoprotein complex and constitutes the major anti-(U1) RNP autoimmune antigen. SNRP70 contains 1 RRM (RNA recognition motif) domain and mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA.
  • Cellular localization
    Nuclear

References for Recombinant Human SNRP70 protein (ab70109)

ab70109 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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