Solute carrier family 9 subfamily A (NHE1 cation proton antiporter 1) member 1
Solute carrier family 9 subfamily A member 1
Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
Kidney and intestine.
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
Phosphorylated upon DNA damage, probably by ATM or ATR. O-glycosylated.