The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml. Best used within three months from the date of receipt.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.3% Glutathione, 0.79% Tris HCl
Na(+)/H(+) exchanger 3
Sodium/hydrogen exchanger 3
Sodium/hydrogen exchanger, apical epithelial
Solute carrier family 9 (sodium/hydrogen exchanger), isoform 3
Solute carrier family 9 (sodium/hydrogen exchanger), member 3
Solute carrier family 9 member 3
Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
Phosphorylated by PKA, which inhibits activity.
Membrane. In intestinal epithelial cells, localizes to the ileal brush border.