Recombinant Human Soluble Liver/Pancreas Antigen protein (ab102021)

Overview

  • Product nameRecombinant Human Soluble Liver/Pancreas Antigen protein
  • Protein lengthFull length protein

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionQ9HD40
    • SpeciesHuman
    • SequenceMGSSHHHHHH SSGLVPRGSH MNRESFAAGE RLVSPAYVRQ GCEARRSHEH LIRLLLEKGK CPENGWDEST LELFLHELAI MDSNNFLGNC GVGEREGRVA SALVARRHYR FIHGIGRSGD ISAVQPKAAG SSLLNKITNS LVLDIIKLAG VHTVANCFVV PMATGMSLTL CFLTLRHKRPKAKYIIWPRI DQKSCFKSMI TAGFEPVVIE NVLEGDELRT DLKAVEAKVQ ELGPDCILCI HSTTSCFAPR VPDRLEELAV ICANYDIPHIVNNAYGVQSS KCMHLIQQGA RVGRIDAFVQ SLDKNFMVPV GGAIIAGFND SFIQEISKMY PGRASASPSL DVLITLLSLG SNGYKKLLKE RKEMFSYLSN QIKKLSEAYN ERLLHTPHNP ISLAMTLKTL DEHRDKAVTQ GSMLFTRQV SGARVVPLGS MQTVSGYTFR GFMSHTNNYP CAYLNAASAI GMKMQDVDLF IKRLDRCLKA VRKERSKESD DNYDKTEDVD IEEMALKLDN VLLDTYQDAS S
    • Molecular weight58 kDa including tags
    • Amino acids1 to 501
    • TagsHis tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab102021 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF
  • Purity> 90 % SDS-PAGE.
    ab102021 was purified using conventional chromatography techniques.
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, 100mM Sodium chloride, 1mM DTT, pH 8.0

General Info

  • Alternative names
    • DKFZp434B1417
    • Liver pancreas antigen
    • Liver-pancreas antigen
    • LP
    • MGC161491
    • O phosphoseryl tRNA(Sec) selenium transferase
    • O-phosphoseryl-tRNA(Sec) selenium transferase
    • Sec synthase
    • Selenocysteine synthase
    • Selenocysteinyl tRNA(Sec) synthase
    • Selenocysteinyl-tRNA(Sec) synthase
    • Sep (O phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
    • Sep tRNA:Sec tRNA synthase
    • Sep-tRNA:Sec-tRNA synthase
    • SepSecS
    • SLA
    • SLA p35
    • SLA-p35
    • SLA/LP
    • SLA/LP autoantigen
    • Soluble liver antigen
    • Soluble liver antigen/liver pancreas antigen
    • SPCS_HUMAN
    • tRNA(Ser/Sec) associated antigenic protein
    • tRNA(Ser/Sec)-associated antigenic protein
    • TRNP48
    • UGA suppressor tRNA associated protein
    • UGA suppressor tRNA-associated protein
    see all
  • FunctionConverts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
  • Tissue specificityPrimarily expressed in liver, pancreas, kidney and lung. Overexpressed in PHA-stimulated T-cells.
  • PathwayAminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; selenocysteinyl-tRNA(Sec) from L-seryl-tRNA(Sec) (archaeal/eukaryal route): step 2/2.
  • Involvement in diseaseDefects in SEPSECS are the cause of pontocerebellar hypoplasia type 2D (PCH2D) [MIM:613811]. PCH2D is a disorder characterized by postnatal onset of progressive atrophy of the cerebrum and cerebellum, microcephaly, profound mental retardation, spasticity, and variable seizures.
  • Sequence similaritiesBelongs to the SepSecS family.
  • Cellular localizationCytoplasm.
  • Information by UniProt

Recombinant Human Soluble Liver/Pancreas Antigen protein images

  • 15% SDS-PAGE analysis of 3 µg ab102021.

References for Recombinant Human Soluble Liver/Pancreas Antigen protein (ab102021)

ab102021 has not yet been referenced specifically in any publications.

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