Recombinant Human Soluble Liver/Pancreas Antigen protein (ab102021)

Overview

  • Product name
    Recombinant Human Soluble Liver/Pancreas Antigen protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MNRESFAAGE RLVSPAYVRQ GCEARRSHEH LIRLLLEKGK CPENGWDEST LELFLHELAI MDSNNFLGNC GVGEREGRVA SALVARRHYR FIHGIGRSGD ISAVQPKAAG SSLLNKITNS LVLDIIKLAG VHTVANCFVV PMATGMSLTL CFLTLRHKRPKAKYIIWPRI DQKSCFKSMI TAGFEPVVIE NVLEGDELRT DLKAVEAKVQ ELGPDCILCI HSTTSCFAPR VPDRLEELAV ICANYDIPHIVNNAYGVQSS KCMHLIQQGA RVGRIDAFVQ SLDKNFMVPV GGAIIAGFND SFIQEISKMY PGRASASPSL DVLITLLSLG SNGYKKLLKE RKEMFSYLSN QIKKLSEAYN ERLLHTPHNP ISLAMTLKTL DEHRDKAVTQ GSMLFTRQV SGARVVPLGS MQTVSGYTFR GFMSHTNNYP CAYLNAASAI GMKMQDVDLF IKRLDRCLKA VRKERSKESD DNYDKTEDVD IEEMALKLDN VLLDTYQDAS S
    • Molecular weight
      58 kDa including tags
    • Amino acids
      1 to 501
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab102021 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF
  • Purity
    > 90 % SDS-PAGE.
    ab102021 was purified using conventional chromatography techniques.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, 100mM Sodium chloride, 1mM DTT, pH 8.0

General Info

  • Alternative names
    • DKFZp434B1417
    • Liver pancreas antigen
    • Liver-pancreas antigen
    • LP
    • MGC161491
    • O phosphoseryl tRNA(Sec) selenium transferase
    • O-phosphoseryl-tRNA(Sec) selenium transferase
    • Sec synthase
    • Selenocysteine synthase
    • Selenocysteinyl tRNA(Sec) synthase
    • Selenocysteinyl-tRNA(Sec) synthase
    • Sep (O phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
    • Sep tRNA:Sec tRNA synthase
    • Sep-tRNA:Sec-tRNA synthase
    • SepSecS
    • SLA
    • SLA p35
    • SLA-p35
    • SLA/LP
    • SLA/LP autoantigen
    • Soluble liver antigen
    • Soluble liver antigen/liver pancreas antigen
    • SPCS_HUMAN
    • tRNA(Ser/Sec) associated antigenic protein
    • tRNA(Ser/Sec)-associated antigenic protein
    • TRNP48
    • UGA suppressor tRNA associated protein
    • UGA suppressor tRNA-associated protein
    see all
  • Function
    Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
  • Tissue specificity
    Primarily expressed in liver, pancreas, kidney and lung. Overexpressed in PHA-stimulated T-cells.
  • Pathway
    Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; selenocysteinyl-tRNA(Sec) from L-seryl-tRNA(Sec) (archaeal/eukaryal route): step 2/2.
  • Involvement in disease
    Defects in SEPSECS are the cause of pontocerebellar hypoplasia type 2D (PCH2D) [MIM:613811]. PCH2D is a disorder characterized by postnatal onset of progressive atrophy of the cerebrum and cerebellum, microcephaly, profound mental retardation, spasticity, and variable seizures.
  • Sequence similarities
    Belongs to the SepSecS family.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of 3 µg ab102021.

References

ab102021 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab102021.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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