Recombinant Human Sorbitol Dehydrogenase protein (ab95892)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionQ00796
    • SpeciesHuman
    • SequenceMGSSHHHHHH SSGLVPRGSH MAAAAKPNNL SLVVHGPGDL RLENYPIPEP GPNEVLLRMH SVGICGSDVH YWEYGRIGNF IVKKPMVLGH EASGTVEKVG SSVKHLKPGD RVAIEPGAPR ENDEFCKMGR YNLSPSIFFC ATPPDDGNLC RFYKHNAAFC YKLPDNVTFE EGALIEPLSV GIHACRRGGV TLGHKVLVCG AGPIGMVTLL VAKAMGAAQV VVTDLSATRL SKAKEIGADL VLQISKESPQ EIARKVEGQL GCKPEVTIEC TGAEASIQAG IYATRSGGTL VLVGLGSEMT TVPLLHAAIR EVDIKGVFRY CNTWPVAISM LASKSVNVKP LVTHRFPLEK ALEAFETFKK GLGLKIMLKC DPSDQNP
    • Molecular weight40 kDa including tags
    • Amino acids1 to 357
    • TagsHis tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab95892 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Purity> 90 % SDS-PAGE.
    ab95892 is purified using conventional chromatography techniques.
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 0.2M Sodium chloride, 5mM DTT, 20mM Tris HCl, pH 8.0

General Info

  • Alternative names
    • DHSO_HUMAN
    • L iditol 2 dehydrogenase
    • L-iditol 2-dehydrogenase
    • OTTHUMP00000161939
    • SDH
    • Sorbitol dehydrogenase
    • Sorbitol dehydrogenase 1
    • SORD
    • SORD 1
    • SORD1
    see all
  • FunctionConverts sorbitol to fructose. Part of the polyol pathway that plays an important role in sperm physiology. May play a role in the sperm motility by providing an energetic source for sperm.
  • Tissue specificityExpressed in kidney and epithelial cells of both benign and malignant prostate tissue. Expressed in epididymis (at protein level).
  • Sequence similaritiesBelongs to the zinc-containing alcohol dehydrogenase family.
  • Cellular localizationMitochondrion membrane. Cell projection > cilium > flagellum. Associated with mitochondria of the midpiece and near the plasma membrane in the principal piece of the flagellum. Also found in the epididymosome, secreted by the epididymal epithelium and that transfers proteins from the epididymal fluid to the sperm surface.
  • Information by UniProt

Recombinant Human Sorbitol Dehydrogenase protein images

  • 15% SDS-PAGE showing ab95892 at approximately 40.4kDa (3µg).

References for Recombinant Human Sorbitol Dehydrogenase protein (ab95892)

ab95892 has not yet been referenced specifically in any publications.

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