Recombinant Human Spasmolytic Polypeptide protein (ab116418)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MKHHHHHHAS EKPSPCQCSR LSPHNRTNCG FPGITSDQCF DNGCCFDSSV TGVPWCFHPL PKQESDQCVM EVSDRRNCGY PGISPEECAS RKCCFSNFIF EVPWCFFPKSVEDCHY
    • Molecular weight
      13 kDa including tags
    • Amino acids
      24 to 129
    • Tags
      His tag N-Terminus
    • Additional sequence information
      TFF-2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 116 amino acids (24-129) which includes a 10 amino acid His Tag fused at N-terminus.

Specifications

Our Abpromise guarantee covers the use of ab116418 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 95 % SDS-PAGE.
    Purified by proprietary chromatographic techniques
  • Form
    Lyophilised
  • Additional notes
    ab116418 is stable at room temperature for 3 weeks, long term it should be stored desiccated below -18°C. Upon reconstitution ab116418 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Please see notes section.

    pH: 7.50
    Constituents: 0.242% Tris, 0.117% Sodium chloride

  • Reconstitution
    Add deionized water to prepare a working stock solution of approximately 0.5mg/ml. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

General Info

  • Alternative names
    • SML 1
    • SML1
    • SP
    • Spasmolysin
    • Spasmolytic polypeptide
    • spasmolytic protein 1
    • TFF 2
    • TFF2
    • TFF2_HUMAN
    • Trefoil factor 2
    • trefoil factor 2 (spasmolytic protein 1)
    • Trefoil factor 2 precursor
    see all
  • Function
    Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains.
  • Tissue specificity
    Stomach.
  • Sequence similarities
    Contains 2 P-type (trefoil) domains.
  • Cellular localization
    Secreted.
  • Information by UniProt

References

ab116418 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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