Recombinant Human Spasmolytic Polypeptide protein (ab116426)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionQ03403
    • SpeciesHuman
    • SequenceEKPSPCQCSR LSPHNRTNCG FPGITSDQCF DNGCCFDSSV TGVPWCFHPL PKQESDQCVM EVSDRRNCGY PGISPEECAS RKCCFSNFIF EVPWCFFPKSVEDCHY
    • Molecular weight12 kDa
    • Amino acids24 to 129

Specifications

Our Abpromise guarantee covers the use of ab116426 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityDetermined by its ability to chemoattract human MCF-7 cells using a concentration 1.0-10.0 ng/ml.
  • Applications

    Functional Studies

    SDS-PAGE

    HPLC

  • Purity> 95 % SDS-PAGE.
    Purified by proprietary chromatographic techniques. Purity greater than 97.0% as determined by RP-HPLC.
  • FormLyophilised
  • Additional notesFor long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Determined by its ability to chemoattract human MCF-7 cells using a concentration 1.0-10.0 ng/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituent: PBS

  • ReconstitutionReconstitute the lyophilized TFF2 in sterile 18MOhm-cm H2O not less than 100µg/ml

General Info

  • Alternative names
    • SML 1
    • SML1
    • SP
    • Spasmolysin
    • Spasmolytic polypeptide
    • spasmolytic protein 1
    • TFF 2
    • TFF2
    • TFF2_HUMAN
    • Trefoil factor 2
    • trefoil factor 2 (spasmolytic protein 1)
    • Trefoil factor 2 precursor
    see all
  • FunctionInhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains.
  • Tissue specificityStomach.
  • Sequence similaritiesContains 2 P-type (trefoil) domains.
  • Cellular localizationSecreted.
  • Information by UniProt

References for Recombinant Human Spasmolytic Polypeptide protein (ab116426)

ab116426 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab116426.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"