Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Molecular weight
      110 kDa including tags
    • Amino acids
      1 to 654

Associated products

Specifications

Our Abpromise guarantee covers the use of ab125634 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    The specific activity of ab125634 was determined to be 30 nmol/min/mg.
  • Applications

    Western blot

    Functional Studies

    SDS-PAGE

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol, 0.88% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • SK 2
    • Sphingosine kinase 2
    • Sphingosine kinase type 2
    • SPHK2
    • SPHK2_HUMAN
    • SPK 2
    see all
  • Function
    Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra-and extracellular functions. Also acts on D-erythro-dihydrosphingosine, D-erythro-sphingosine and L-threo-dihydrosphingosine. Binds phosphoinositides.
  • Sequence similarities
    Contains 1 DAGKc domain.
  • Cellular localization
    Cytoplasm. Membrane and Lysosome membrane.
  • Information by UniProt

Images

  • The purity of ab 125634 was determined to be >80% by densitometry.
  • The specific activity of ab125634 was determined to be 30 nmol/min/mg.

References

ab125634 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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