Recombinant Human SPRR1b protein (ab114941)

Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MSSQQQKQPCIPPPQLQQQQVKQPCQPPPQEPCIPKTKEPCHPKVPEPCH PKVPEPCQPKVPEPCHPKVPEPCPSIVTPAPAQQKTKQK
    • Molecular weight
      36 kDa including tags
    • Amino acids
      1 to 89

Associated products

Specifications

Our Abpromise guarantee covers the use of ab114941 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • 14.9 kDa pancornulin
    • Cornifin
    • Cornifin B
    • Cornifin-B
    • CornifinB
    • GADD33
    • MGC61901
    • Small proline rich protein IB
    • Small proline-rich protein IB
    • SPR-IB
    • SPR1B_HUMAN
    • SPRIB
    • SPRR1
    • SPRR1B
    see all
  • Function
    Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage.
  • Tissue specificity
    Suprabasal layers of squamous-differentiated tissues such as epidermis, esophagus, tongue and trachea.
  • Sequence similarities
    Belongs to the cornifin (SPRR) family.
  • Developmental stage
    Expressed during differentiation of squamous cells.
  • Post-translational
    modifications
    The N-terminus is blocked.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt

Images

  • ab114941 analyzed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

References

ab114941 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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