Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MGS MAYPGHP GAGGGYYPGG YGGAPGGPAF PGQTQDPLYG YFAAVAGQDG QIDADELQRC LTQSGIAGGY KPFNLETCRL MVSMLDRDMS GTMGFNEFKE LWAVLNGWRQ HFISFDTDRS GTVDPQELQK ALTTMGFRLS PQAVNSIAKR YSTNGKITFD DYIACCVKLR ALTDSFRRRD TAQQGVVNFP YDDFIQCVMS V
    • Molecular weight
      24 kDa including tags
    • Amino acids
      1 to 198
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab104927 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Mass Spectrometry

    SDS-PAGE

  • Mass spectrometry
    MALDI-TOF
  • Purity
    > 90 % SDS-PAGE.
    ab104927 was purified using conventional chromatography.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 40% Glycerol, 200mM Sodium chloride, 20mM Tris HCl, 1mM DTT, 0.1mM PMSF, pH 8

General Info

  • Alternative names
    • 22 kDa protein
    • Calcium binding protein amplified in mutlidrug resistant cells
    • CP 22
    • CP-22
    • CP22
    • SCN
    • Sorcin
    • Sorcin (class 4 gene)
    • SORCN_HUMAN
    • SRI
    • V19
    see all
  • Function
    Calcium-binding protein that modulates excitation-contraction coupling in the heart. Contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Modulates the activity of RYR2 calcium channels.
  • Tissue specificity
    Detected in cardiac myocytes.
  • Sequence similarities
    Contains 4 EF-hand domains.
  • Cellular localization
    Cytoplasm. Sarcoplasmic reticulum membrane. Relocates to the sarcoplasmic reticulum membrane in response to elevated calcium levels.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of 3ug ab104927

References

ab104927 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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