Overview

Description

  • NatureRecombinant
  • SourceBaculovirus
  • Amino Acid Sequence
    • AccessionQ15208
    • SpeciesHuman
    • Molecular weight81 kDa including tags

Associated products

Specifications

Our Abpromise guarantee covers the use of ab101549 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityThe Specific activity of ab101549 was determined to be 4 nmol/min/mg.
  • Applications

    Functional Studies

    SDS-PAGE

  • Purity> 70 % SDS-PAGE.
    The purity was determined to be >75% by densitometry
  • FormLiquid
  • Additional notes

    ab204869 (PKI-alpha peptide) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • NDR
    • NDR 1
    • Ndr Ser/Thr kinase-like protein
    • NDR1
    • NDR1 protein kinase
    • Nuclear Dbf2 related kinase 1
    • nuclear Dbf2-related 1
    • Nuclear Dbf2-related kinase 1
    • Nuclear Dbf2-related protein
    • Serine/threonine protein kinase 38
    • Serine/threonine-protein kinase 38
    • STK 38
    • STK38
    • STK38_HUMAN
    see all
  • FunctionNegative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its nonphosphorylated form and inhibits autophosphorylation of MAP3K2.
  • Tissue specificityUbiquitously expressed with highest levels observed in peripheral blood leukocytes.
  • Sequence similaritiesBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications
    ISGylated.
  • Cellular localizationNucleus. Cytoplasm.
  • Information by UniProt

Recombinant human STK38 protein images

  • SDS-PAGE showing ab101549 at approximately 81kDa.
  • Kinase Assay demonstrating specific activity of ab101549.

References for Recombinant human STK38 protein (ab101549)

ab101549 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"