Overview

Description

  • NatureRecombinant
  • SourceBaculovirus infected Sf9 cells
  • Amino Acid Sequence
    • AccessionQ6J9G0
    • SpeciesHuman
    • Molecular weight67 kDa including tags
    • Amino acids58 to 422

Associated products

Specifications

Our Abpromise guarantee covers the use of ab125536 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    SDS-PAGE

  • Purity> 70 % Densitometry.
    Purity determined to be >70% by densitometry.
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol, 0.29% Sodium chloride

General Info

  • Alternative names
    • DKFZp761P1010
    • NOK
    • Novel oncogene with kinase domain
    • Protein kinase STYK1
    • Protein PK unique
    • Protein PK-unique
    • Serine/threonine/tyrosine kinase 1
    • Styk 1
    • STYK1
    • STYK1_HUMAN
    • SuRTK 106
    • SuRTK106
    • Tyrosine protein kinase STYK1
    • Tyrosine-protein kinase STYK1
    see all
  • FunctionProbable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways.
  • Tissue specificityWidely expressed. Highly expressed in brain, placenta and prostate. Expressed in tumor cells such as hepatoma cells LO2, cervix carcinoma cells HeLa, ovary cancer cells Ho8910 and chronic myelogenous leukemia cells K562, but not in other tumor cells such as epidermoid carcinoma (A431). Undetectable in most normal lung tissues, widely expressed in lung cancers.
  • Sequence similaritiesBelongs to the protein kinase superfamily. Tyr protein kinase family.
    Contains 1 protein kinase domain.
  • Cellular localizationMembrane.
  • Information by UniProt

Recombinant Human Styk1 protein images

  • SDS-PAGE analysis of ab125536.

References for Recombinant Human Styk1 protein (ab125536)

ab125536 has not yet been referenced specifically in any publications.

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