Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MQVQRRKWKL NLIAELESRV LAEPVPLPAD PMELKNLEYR PVKVRGCFDH SKELYMMPRT MVDPVREARE GGLISSSTQS GAYVVTPFHC TDLGVTILVN RGFVPRKKVN PETRQKGQIE GEVDLIGMVR LTETRQPFVP ENNPERNHWH YRDLEAMARI TGAEPIFIDA NFQSTVPGGP IGGQTRVTLR NEHLQ
    • Molecular weight
      24 kDa including tags
    • Amino acids
      80 to 273
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab117647 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 95 % SDS-PAGE.

  • Form
    Liquid
  • Additional notes
    Surf1 protein although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride, 0.02% DTT, 20% Glycerol

General Info

  • Alternative names
    • OTTHUMP00000022473
    • OTTHUMP00000022474
    • SURF 1
    • SURF-1
    • Surf1
    • SURF1_HUMAN
    • Surfeit 1
    • Surfeit locus protein 1
    see all
  • Function
    Probably involved in the biogenesis of the COX complex.
  • Involvement in disease
    Defects in SURF1 are a cause of Leigh syndrome (LS) [MIM:256000]. LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions that is commonly associated with systemic cytochrome c oxidase (COX) deficiency.
  • Sequence similarities
    Belongs to the SURF1 family.
  • Cellular localization
    Mitochondrion inner membrane.
  • Information by UniProt

References for Recombinant Human Surf1 protein (ab117647)

ab117647 has not yet been referenced specifically in any publications.

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