May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca(2+)-dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface.
Belongs to the synaptotagmin family. Contains 2 C2 domains.
Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Recycling endosome membrane. In mast cells, localizes to the endocytic recycling compartment.
SDS-PAGE - Synaptotagmin V protein (Tagged-His Tag) (ab91737)
The image shows an electrophoretic assay performed using an Agilent 5100 ALP. In some images coloured control bands can be seen at 15 kDa (green) and/or 240 kDa (purple). The protein-specific band is blue.
has not yet been referenced specifically in any publications.
Publishing research using ab91737? Please let us know so that we can cite the reference in this datasheet.
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