Recombinant Human Syntaxin 4 protein (ab114464)

Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      DKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQELEKQQVT ILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADENYNSV N
    • Molecular weight
      37 kDa including tags
    • Amino acids
      19 to 119

Specifications

Our Abpromise guarantee covers the use of ab114464 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
    ab114464 is best used within three months from the date of receipt.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris buffered saline, 0.3% Glutathione

General Info

  • Alternative names
    • NY REN 31 antigen
    • p35 2
    • PLACENTAL
    • Renal carcinoma antigen NY REN 31
    • Renal carcinoma antigen NY-REN-31
    • Stx4
    • STX4_HUMAN
    • STX4A
    • Syntaxin 4
    • Syntaxin 4A
    • syntaxin 4A (placental)
    • Syntaxin-4
    see all
  • Function
    Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity). May also play a role in docking of synaptic vesicles at presynaptic active zones.
  • Tissue specificity
    Expressed in neutrophils and neutrophil-differentiated HL-60 cells. Expression in neutrophils increases with differentiation.
  • Sequence similarities
    Belongs to the syntaxin family.
    Contains 1 t-SNARE coiled-coil homology domain.
  • Cellular localization
    Cell membrane.
  • Information by UniProt

Images

  • ab114464 analysed on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab114464 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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