Recombinant human TAK1 + TAB1 protein (ab89692)

Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Species
      Human

Specifications

Our Abpromise guarantee covers the use of ab89692 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    The Specific activity of ab89692 was determined to be 10 nmol/min/mg.
  • Applications

    SDS-PAGE

    Western blot

    Functional Studies

  • Form
    Liquid
  • Additional notes

    ab64311 (Myelin Basic Protein protein) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • 2310012M03Rik
    • 3' Tab1
    • B430101B05
    • C87327
    • MAP3K7
    • MAP3K7IP1
    • MEKK7
    • MGC57664
    • Mitogen activated protein kinase kinase kinase 7
    • Mitogen activated protein kinase kinase kinase 7 interacting protein 1
    • Mitogen-activated protein kinase kinase kinase 7-interacting protein 1
    • RP23-447J12.1
    • TAB1
    • TAB1_HUMAN
    • TAK1 binding protein 1
    • TAK1-binding protein 1
    • TGF beta activated kinase 1
    • TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
    • TGF-beta-activated kinase 1-binding protein 1
    • TGF1a
    • Transforming growth factor beta activated kinase 1
    • Transforming growth factor beta activated kinase binding protein 1
    see all
  • Function
    May be an important signaling intermediate between TGFB receptors and MAP3K7/TAK1. May play an important role in mammalian embryogenesis.
  • Tissue specificity
    Ubiquitous.
  • Sequence similarities
    Contains 1 PP2C-like domain.
  • Post-translational
    modifications
    Monoubiquitinated. Deubiquitinated by Y.enterocolitica YopP.
  • Information by UniProt

Images

  • SDS-PAGE showing ab89692 at approximately 74kDa.
  • Kinase Assay demonstrating specific activity of ab89692.

References

ab89692 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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