Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Species
      Human
    • Amino acids
      1 to 314

Associated products

Specifications

Our Abpromise guarantee covers the use of ab63169 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    Specific activity: 1670 nmol/min/mg.
  • Applications

    Functional Studies

    SDS-PAGE

  • Form
    Liquid
  • Additional notes

    ab64311 (Myelin Basic Protein protein) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • 2810468K05Rik
    • AU020252
    • D130018F14Rik
    • EC 2.7.11.1
    • FLJ14314
    • hKFC B
    • hKFC-B
    • KIAA1361
    • Kinase from chicken homolog B
    • MAP3K16
    • MARK kinase
    • MARKK
    • MGC29021
    • Microtubule affinity regulating kinase kinase
    • mKIAA1361
    • Prostate-derived sterile 20-like kinase 2
    • PSK2
    • Serine/threonine kinase TAO1
    • Serine/threonine protein kinase TAO1
    • Serine/threonine protein kinase TAO1 homolog
    • Serine/threonine-protein kinase TAO1
    • STE20 like kinase
    • STE20 like kinase PSK2
    • STE20-like kinase PSK2
    • TAO kinase 1
    • Taok1
    • TAOK1_HUMAN
    • Thousand and one amino acid protein 1
    see all
  • Function
    Phosphorylates MKK3 (By similarity). Activates the p38 MAP kinase pathway through the specific activation of the upstream MKK3 kinase.
  • Tissue specificity
    Highly expressed in the testis, and to a lower extent also expressed in brain, placenta, colon and skeletal muscle.
  • Sequence similarities
    Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications
    Autophosphorylated.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt

Images

  • Sample Kinase Activity Plot.
  • ab63169 on SDS-PAGE. Molecular Weight: ~63 kDa.

References

ab63169 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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